医学精品课件：05&06.Steven Johnson syndrome.pptx

1、Stevens-Johnson Syndrome and moreWANG Li1st Hospital,Chongqing Medical University2017-3-22Introduction Disease Background Reading&Analysis Summary 4123OutlinesIntroduction -Medical abstract -How to find medical abstract Page 81 Three steps Useful website www.ncbi.nlm.nih.govwww.ncbi.nlm.nih.gov Step

2、 1Input keywords-Step 2Read&decision-Step 3Example Trend to find new molecular markers of DLBCLWhat is Stevens Johnson Syndrome?u May be called:Toxic Epidermal Necrolysis Syndrome u Major Discovered in 1922 by Dr.A.M.Stevens and S.C.Johnson,pediatricians u Fatal in 15%of cases n A severe,life threat

3、ening drug reactionn Manifested by multiple lesions on skin,mucous membranes and conjunctivan May permeate to lungs and kidneys and other organs,increasing severity of illnessDefinitionP111Vocabulary Reepithelialization Re-epithelial-lization Ventriculovenous Ventricle 脑室，心室 Ventricular adj Venous 静

4、脉的u Xenograft heterograftu Homograftu TransplantationHSCT-definitionDefinition a medical procedure in the fields of hematology and oncology,the recipients hematologic and immune system are usually destroyed with radiation or chemotherapy before the transplantation,then donors HSCs are infused into r

5、ecipients body to reconstitute hematologic system and immune system.ConditioningTransplantation Post transplantHSC mobilizing CollectingProcedures of HSCTDRExcepta Medica -荷兰荷兰医学文摘医学文摘Excepta Medica DatabaseExcepta Medica Foundation16 million population 4.2万平方公里 Systemic lupus erythematosus（SLE）l Sy

6、stemic Lupus erythematosus(SLE)is a syndrome of unknown etiology most commonly affecting young women.Virtually any organ of the body may be involved.l Typically the course of the disease is a series of remissions and exacerbations.l With good management,the ten years survival may be over 90%.P112Voc

7、abulary Migrain -migrainous Positron emission tomography PET Corticosteroid corticoid-steroidDefinition of Peptic ulcer Peptic ulcer disease(PUD)=Mucosa defect in the gastrointestinal tract(gastric or duodenal)exposed to acid and pepsin secretion.Gastritis is the precursor to PUD and it is clinicall

8、y difficult to differentiate the two Treatment non-H.Pylori Antacid H2 receptor antagonists (H2-Blockers)Proton Pump Inhibitors(PPI)BismuthTriple therapy for 14 days is treatment of choiceH.Pylori Triple Therapy Treatment PPIbased or bismuth-basedAntibiotics(2 of 3)PPI-based=PPI+2 antibiotics for 2

9、weeks,cont PPI for additional 2 weeks Bismuth-based=bismuth and 2 antibiotics,for 2 weeks with addition of H2-blocker to optimize ulcer healingAmoxicillin1000mg bidMetronidazole400mg bidClarithromycin500mg bidGoal:completely elimination of H.pyloriSuffixVagotomyvagus nerve-sympathetic nerve 交感神经-tom

10、y(removal)Craniotomy 开颅术 lobectomy 肺叶切除术 splenectomy 脾脏切除术 appendectomy 阑尾切除术 -graphy（照像术）cephalography 测颅术 cardiography 心动描记法-gram imaging cardiogram 心动图 -scope(glass)ophthalmoscope 检眼镜 stethoscope 听诊器 microscope telescope -cyte(cell)leukocyte monocyte-coccus 球菌球菌 staphylococci its plural：cocci 葡萄球

11、菌 meningococci 脑膜炎球菌 pneumococci 肺炎球菌 streptococci 链球菌-itis inflammation hepatitis bronchitis nephritis colitis colon gastritis appendicitis otitis 中耳炎 endocarditis 心内膜炎 Vocabulary Dump-dumping 倾倒 vt的现在分词 Prepyloric pre-pyloric 幽门前的Dumping syndrome a group of symptoms that are most likely to develop if oneve had surgery to remove all or part of ones stomach.Also called rapid gastric emptying,it occurs when the undigested contents of your stomach move too rapidly into your small bowel.Common symptoms include abdominal cramps,nausea and diarrhea.