组胚学英文版课件Cardiovascular-System.ppt
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- 组胚学 英文 课件 Cardiovascular System
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1、组胚学英文版课件Cardiovascular System-Digestive system:nDigestive tract nDigestive gland1.Components of digestive tract-oral cavity -pharynx-esophagus-stomach-small intestine-large intestine2.General structure of digestive tractmucosa,submucosa,muscularis externa,adventitia1)mucosa -epithelium:n stratified
2、squamous epi.n simple columnar epi-lamina propria:LCT-compact CT:contain more cells and fibernBV,LV-capillariesnLymphoid Tnglands:structures formed by invagination of epi.into lamina propria-muscularis mucosa:a thin layer of SM2)submucosa:more dense CTnsmall artery and vein,LVnglands(esophagus and d
3、uodenum)nsubmucosa N plexus:-multipolar N -unmyelinated NF -function:regulate the contract of SM and secreting of gland*Plica:projection of mucosa and submucosaPlicamucosa&submucos 3)muscularis externan smooth musclen skeletal musclen inner circular and outer longitudinal*Nerve plexus:regulate the m
4、ovement of M 4)adventitia:CTn serosa:CT+mesotheliumn fibrosa:LCTNerve plexus between layers of muscularis ncell body of nerve cellsserosafibrosa3.Esophagus 1)mucosa:nepithelium:stratified squamous epi.nlamina propria:compact CTnmuscularis mucosa:longitudinal arranged SM 2)submucosa:n LCTn esophageal
5、 gland:mucous gland 3)muscularis:ninner circular and outer longitudinalnupper 1/3:skeletal musclenmiddle 1/3:mixed of skeletal M and smooth musclenlower 1/3:smooth muscle 4)adventitia:fibrosaCross sectionHE Slide:mucosa&submucosBarrett Esophagus is a chronic complication of gastroesophageal reflux d
6、isease(GERD),characterized by metaplasia of the stratified squamous epithelium of the lower esophagus into a specialized glandular epithelium with goblet cells.And the inflammatory cells(mainly lymphocytes and plasma cells)are infiltrating the connective tissue.Esophageal Carcinoma is a malignant ne
7、oplasm that stems from the epithelial cells lining the inner surface of the esophagus.Worldwide,squamous cell carcinoma is the most common type of esophageal.Pathological changes include ulcerations,exophytic masses,and thickening and narrowing of the lumen.This photomicrograph shows a moderately di
8、fferentiated squamous cell carcinoma with focal keratin production in the center,called a keratin pearl.4.Stomach-dilated part-store food temporarily-digest protein primarily-absorb part of water and ionsGeneral structureStomachMucosa:-plica-longitudinal-shallow ditch-gastric area(2-6mm)-gastric pit
9、-small depressions Stomachepithelium:simple columnar episurface mucous cell:-tall columnar-N ovoid,basally-located-mucinogen granule-tight junction-high HCO3-undissolved mucus Stomachlamina propria:CT contains fibroblast,LC,plasma cell,mast cell and eosinophil,SM gastric gland(fundic gland)-oxyntic
10、gland cardiac gland:mucous gland pyloric gland:mucous glandparietal cell-LM:large,pyramidal or spherical/round centrally-located nucleus/eosinophilic cytoplasmEM:n intracellular s e c r e t o r y canaliculus-invaginationsn tubulovesicular systemn mitochondria-function:i.secret hydrochloric acid(HCl)
11、-synthesis processes of HCl:in intracellular secretory canaliculusnH+K+-ATP pump:get H+from cellnCl-channel:get Cl-from bloodnH+Cl-HCl(intracellular secretort canaliculi)-function of HCl:n HCl pepsinogenpepsinnkill the bacterium ii.secret intrinsic factor-glycoprotein+VB12absorption of VB12 a.chief
12、cell or zymogenic cell-structure:LM:ncolumnar nRound,basally-located Nucleusncytoplasm:/basal-basophilic /apical-zymogen granulesEM:RER,Golgi apparatus-f u n c t i o n:s e c r e t pepsinogenc.mucous neck cellnless,neck partncolumnar nflattened,basally-located Nnpale stain in HE staind.stem cell:undi
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