医学精品课件：第十六章营养膳食与疾病.ppt

1、营养膳食与疾病,慢性非传染性疾病 的预防与控制,改变生活方式可以预防高血压，这是一条经济、简便、有效途径 JNC7: 生活方式调整 预防和控制高血压 JNC7：美国预防、检测、评估与治疗 高血压全国联合委员会第七次报告,蔬菜水果和血压, 血胆固醇,高血压是心脏病和脑中风的第一位的危险因素 控制血压十分重要, 膳食对控制血压相当有效. Dietary Approaches to Stop Hypertension (DASH) study 富含蔬菜水果; 低脂肪(饱和脂肪,总脂肪) 饮食 收缩压(高压) 11 mm Hg 舒张压 (低压) 6 mm Hg - 和降压药的效果类似,150,160,

2、170,180,190,200,210,220,0,10,20,30,（,day,）,(,m,m,Hg,),Control vs. BTP treated group： * p0.05 Control vs. GTP treated group ： p0.05,*,*,茶多酚对SHRSP 收缩压的影响,Control,GTP treated group,Data by Dr. Negishi H J Nutrition 2004; 134: 38,SHRSP （Stroke-Prone spontaneously hypertensive Rat),Risk Factors for CHD,M

3、odifiable Dyslipidemia Raised LDL Low HDL Raised TGs Smoking Hypertension Diabetes mellitus Obesity Dietary factors Thrombogenic factors Sedentary lifestyle,Non-modifiable Family history of premature CHD Age Sex,Smoking,Serum total cholesterol level (240 mg/dL OR 6.2 mmol/L),Hypertension (DBP 90 mm

4、Hg),x2.5,x7,x11,x6,x3,x3,x3,Relationship between Cholesterol and CHD risk: The Framingham Study,0,25,50,75,100,125,150,204,205-234,235-264,265-294,295,CHD incidence per 1000,Serum cholesterol (mg/100 mL),mg/dL x 0.0259= mmol/L,(Adapted from Verschuren et al., 1995),Serum total cholesterol (mmol/l),35,30,25,20,15,10,5,0,Death rate from CHD/1000 men,2.60,3.25,3.90,4.50,5.15,5.80,6.45,7.10,7.75,8.40,9.05,Northern Europe,United States,Southern Europe, inland,Southern Europe, Mediterranean,Japan,Serbia,多酚消费和冠心病的关系,北欧 2.6 mg/d 克罗地亚 13.1mg/d 日本 68.2 mg/d,