小儿科药物剂量课件.ppt

1、可编辑ppt1三軍總醫院 小兒部Instructor:R2王聖儒可编辑ppt2 010Kg(4 MD/kg)：100ml/kg/day 1020kg(2 MD/kg)：1000(BW10)50/day 20kg (1 MD/kg)：1500(BW20)20/dayExample 1:BW=25 kg,Keep IV route with 0.33%G/S _MD/minAns:(10 4)+(10 2)+(5 1)=65 MD/minExample 2:BW=30 kg,Keep IV route with 0.33%G/S _MD/min _c.c.qdAns:(10 4)+(10 2)+(

2、10 1)=70 MD/min (10 100)+(10 50)+(10 20)=1700 c.c./day可编辑ppt3 10%(severe):Lethargy or Coma,Sunken anterior frontanelle and eyes,Cold extremities,Weak or impalpable pulse,Hypotension 可编辑ppt4 Rehydration:First 8 hr Later 16 hr Deficit 1/2 1/2 Maintenance 1/3 2/3 e.g.:10kg,10%loss,3 days Deficit:10%x 1

3、0(kg)x 0.6(deficit%from ECF)X 1000=600 ml Maintenance:10 x 100 =1000 ml First 8 hr later 16 hr Deficit 300ml 300ml Maintenance 333ml 660ml 可编辑ppt5:20ml/kg N/S or Lactate Ringers or 10ml/kg 5%albumin,blood,plasma Loading speed:10ml/kg/hr,(2ml/kg/hr in CHF)可编辑ppt6 Na：34 mEq/kg/day 3%NaCl 1ml=0.5 mEq 0

4、.9%NaCl 500ml=77mEq K：23 mEq/kg/day 15%KCl 1ml2 mEq Ca：2001000 mg/kg/day q8h-qd 10%Ca gluconate(100mg/1ml,1Amp10ml)NaHCO3：1 mEq/kg(if PH7.2)17 mEq/20cc/amp 可编辑ppt7Tachypnea(BE=PCO2 1.5 x HCO3+8 2)BE HCO3 Mild 17 Observation Moderate 10-20 17-8 Slow correction Severe 20 7 7%NaHCO3(17 mEq/20ml)supply

5、half in 2-8 hours:2-4 mEq/kg/doseBE x 0.3 x BW(15-HCO3)x 0.6 x BW可编辑ppt8 20kg：錠劑磨粉 40Kg：1#po qid 30Kg：1#po tid 若可吞,不用磨 20Kg：1/2#po qid 10Kg：1/4#po qid 20kg：糖漿可编辑ppt9 Scanol(500mg/1#)：1015mg/kg/dose q4hq6h(50 mg/kg/day)Antiphen(Acetaminophen syrup)：BW/2 q4h prn if BT(120mg/kg/dose)Macsafe(Ibuprofen s

6、yrup)：NSAIDs 38.5:BW/4 cc q6h；:BW/2 cc q6h Diclofen(supp)(12.5mg)：6kg 1/3#supp q6h prn if BT 39.5 610kg 1/2#supp q6h prn if BT 39.5 10kg 1#supp q6h prn if BT 39.5 可编辑ppt10 Medicon-A(20mg/cap):Common dose Medicon syrup(Dextromethorphan)(2.5mg/ml)：BW/4 cc po qid,1-2mg/kg/day q6-8h Mucosolven(Ambroxol

7、liq.)(3mg/ml)(化痰):BW/4 cc qid;止咳):BW/4 cc qid;26y/o:2.55 cc qid;612y/o 510cc qid 可编辑ppt11 Cyproh syrup(Cyproheptadine 0.4 mg/ml)：BW/4 cc po qid Cyproh tablet(嗜睡,增加食慾)：Common dose Demin(Chlorpheniramine 0.5mg/ml)：BW/4 cc po qid CTM tablet(嗜睡,使痰更濃)：Common dose Venalin(Diphenhydramine 30mg/amp):10-50mg

8、 IV or IM q2-3h,max 400mg/day(1mg/kg/dose)Urticaria,angioedema or EPS時可用時可用可编辑ppt12 Clarityne(10mg/tab)：30kg 1/2#po qd；30kg 1#po qd Clarityne syrup(Loratadine 1mg/ml 60ml)30kg 5ml po qd；30kg 10ml po qd Allegra(60mg tab)：1#bid-1#qd可编辑ppt13 Bricanyl(Terbutaline 2ml/5mg):20Kg:1#in N/S 3ml for neubriliz

9、ation q6h Ventolin(Salbutamol neubule 2.5ml/5mg):The same with Bricanyl;Tab(2mg):0.1 mg/kg/dose up to 2 mg PO tid Berotec(Fenoterol HBr)syrup(0.5mg/ml):BW/4BW/5 cc tid;1 y/o:2.5 cc bid;16y/o:2.55 cc tid;614y/o 5cc tid Meptin(Procaterol)syrup(mg/ml):6y/o:5 cc po q12h 可编辑ppt14 Xidanef(Ketotifen)100 ml

10、 syrup:2.5-5ml bid Atrovent(Ipratropium UDV 0.5mg/2ml):1 vial q6h prn Epinephrine(1:1000)：0.01ml/kg/dose(Max 0.5ml)q15minSC 可编辑ppt15 Aminophylline S.E：nausea,vomiting,insomnia,tachycardia Loading dose：5(26)mg/kg/dose iv drip for 2030 min;Maintain：1mg/kg/hr Infants=0.20.9mg/kg/hr,1-9y/o=11.2mg/kg/hr;

11、9-16y/o=0.81mg/kg/hr;youngsmoker:0.81mg/kg/hr,nonsmoker:0.50.7mg/kg/hr Apnea of prematurity：46mg/kg iv 30 min,then maintaince:1.53 mg/kg/dose iv q8-12h 可编辑ppt16 Ventol:3ml/kg/day qid Aminophylline tab.：200mg/tab po qid;dose=iv form 可编辑ppt17 Decadron：0.1 mg/kg/dose im q8h.Rinderon(4mg/ml):0.1 mg/kg/d

12、ose im,iv q8h Prednisolone(5mg/tab):12mg/kg/day po qdqid;max:4#8#(2040)mg/day for 35 day.40kg給Pulmicort(steroid,200mcg/dose)：12 puff bid for 3 month for prevent asthma(可有效預防氣喘再發)可编辑ppt18 Benadryl(Diphenhydramine):1mg/kg IM Decardon(Dexamethasone):0.1mg/kg/dose IM Periactin tab：普通劑量普通劑量 po qid.Predni

13、solone(5mg/tab.):12 mg/kg/day可编辑ppt19 Kaopectin：6 mons：3 po qid（嚴重再給嚴重再給）6 mons6 Y/O：5 po qid 6 Y/O：10 po qid.Biofermin tab：普通劑量普通劑量2 2 po qid.Simethicone tab：普通劑量普通劑量 po qid.Bismuth:普通劑量普通劑量po qid.可编辑ppt20 Motilium(10 mg/tab)：普通劑量普通劑量 po qid.Prepulsid：0.10.2mg/kg/dose po qid Novamine or Priperam ma

14、y cause EPS EPS：Akineton=Biperidine(1#=2mg;5mg/1cc/amp)Adult：2mg per 30 min.max 4 vial(20mg)可编辑ppt21 Glycerine ball enema：0.51#qd MgO tab：普通劑量普通劑量 po qid.Ducolax(Bisacodyl 5mg tab)：612 yo 1#po st.Cascara(Cascara sagrada)：12#po qhs可编辑ppt22 Valium(Diazepam)(10mg/2/amp):5y/o:the same as above except(ma

15、x 10 mg)adolescents:5-10 mg/dose;max:30mg.Neuropam(Lorazepan)(2mg/ml/amp);中效(10-15 hrs)：0.03-0.1mg/kg/dose q1520min 2 dose max:4mg/dose可编辑ppt23 Dilantin(phenytoin)(250mg/5cc/amp)：Loading 1020mg/kg iv with rate1mg/kg/min,max50mg/min,Maintain 5mg/kg/day iv q12h,(不可加於不可加於Glucose solutionGlucose solutio

16、n)Luminal(Phennobarbital)(100mg/cc/amp;32mg/1#)Loading 20mg/kg iv with rate30mg/min;Maintain 5-10mg/kg/day to achieve serum level 40 ug/ml Chloral hydrate enema(10%30ml)：Neonates:25-50 mg/kg/dose,Children:25-100mg/kg/dose 1/23/4 BW cc enema 可编辑ppt24 Penicillin:Bctereimia:2.5-5;Meningitis 7.5-10;infe

17、ction 10-25(單位：萬u/kg/dose q4-6h)Ampicillin:IV 100mg/kg/day,q6h.Amoxicillin Cap(500mg):(Ac.tonsillitis,AOM)Hiconcil Cap(250mg)=50 mg/kg/day q8h.Amoxicillin syrup=BW/2 po q8h.Augmentin(amoxicillin+clavulanic acid,375mg/1#,600mg/vial):BW/2 po q8h.可编辑ppt25 Cephazolin(Veterin):IV 100mg/kg/day,q6h.Keflex(

18、250mg/1#,Cephalexin 1,Ceflexin 500mg/1#):25-50 mg/kg/day poq6h for G(+).Keflor(2 Cefaclor,250 mg/1#,125mg/5cc/60cc/susp)50 mg/kg/day q8h.;BW/2 q8h.(AOM)Zinacef(2 Cefuroxime,250mg,750mg):2mg:250mg/dose po bid Zinnat(2 Cefuroxime,25mg/ml)AOM:2 y/o 10ml q12h Common infection:5ml q12h Rocephin,Syntrix(3

19、Ceftriaxone 500mg/5cc/vial):50-100mg/kg/day iv q12h-qd;Meningitis:100mg/kg/day q12h(max:4g/day)Prostaphlin(Oxacillin):IV 100mg/kg/day,q6h.(Cellulitis)可编辑ppt26 Erythromycin(Mycoplasma,Chlamydia,Legionella)Erythrocin syrup(40mg/cc)：BW/4 cc po q6h Ilosone(250/1#):30-50 mg/kg/day q6h.(20kg 1#qid,40kg 2#

20、qid)Zithromax(Azithromycin,250mg/1#,200mg/5cc/susp)child:1#qd*3day(40kg:2#)Zithromax syrup：BW/4 cc po qd*3 days Klaricid(Clarithromycin,250/tab):Adult 12#po bid;Child:7.5mg/kg bid可编辑ppt27 Nitrofurantoin(Ninru,100mg/1#)：57mg/kg/day,po qid(UTI),Adult:1#po qid.Prophylactic dose:1/31/4 therapeutic dose

21、Azactam(Aztreonam 1 g/inj):90-120mg/kg/day iv q6-8h for G(-)and Pseudomonas Mycostatin(50萬u/1#):for Candida(Oral thrush):Infant:2/5#(20萬u)/dose q6h Child:1#(40-60u)/dose q6h Baktar(TMP-80+SMX-400):6-12 mg/kg/day po q12h(Contraindication 1y/o;0.075-0.15 mg/kg,slow IV,repeat twice q15m可编辑ppt29 Aspirin

22、(500mg/13):Analgesic:10-15 mg/kg/dose po q6-8h Anti-rheumatic:65-100mg/kg/day po q6-8h Kawasaki disease:100mg/kg/day po q6h Indocin:Dose:No.1 No.2 No.3 7 days-0.2 0.1 0.25 可编辑ppt30 Lasix(40mg/1#,20mg/2cc/inj):1-2mg/kg/dose q6-12h Mannitol(60mg/20%/300cc):0.5-1.0g/kg/dose iv for 30min Insulin:DKA:0.0

23、5-0.1u/kg/hr iv drip,maintain：0.5-1u/kg/day/SC Glucose intolerance in prematurity:0.01-0.1u/kg/hr.Difflam Anti-Inflammatory Spray（得伏寧（得伏寧 消炎噴液劑）消炎噴液劑）成份：每成份：每mL含含Benzydamine Hydrochloride 15 mg 作用：作用：Benzydamine為一抗炎止痛劑，可舒解口腔及咽喉疼痛。為一抗炎止痛劑，可舒解口腔及咽喉疼痛。用法：直接噴用法：直接噴5-10次於疼痛和發炎部位，再輕輕吞下，視需要，可每次於疼痛和發炎部位，再輕輕

24、吞下，視需要，可每1.5-3小時重覆一次。小時重覆一次。可编辑ppt31 E-T tube size：Newborn：2.5 4 Fr;2 Y/O=4(age/4)Fr Depth:lip-tip length(about3*E-T tube size)Depth:1/2/3/4 kg 7/8/9/10 cm Epinephrine(1：1000)：(1mg1ml)0.01 ml/kg/dose iv;or 0.1 ml/kg/dose via ET tube Dopamine：(6BW)kg in N/S final V100ml 1MD/min1ug/kg/min N.E.(Levophe

25、d):1mg/ml;0.05-0.1ug/kg/min drip.Nitroprusside(Nipride):0.5-1.0 ug/kg/min drip.可编辑ppt32 Atropine：0.02mg/kg(1ml0.1mg)q5m,total max dose:child=1mg,adolescent:2mg;minimal dose=0.1mg NaHCO3：1 meq/kg(if PH7.2)Lidocaine(10mg/ml):1mg/kg loading,20-50ung/kg/min,(60 xBW)mg of lidocaine dilute with N/S to 100ml,then 1MD/min10ug/kg/min Adenosine:for PSVT Neonates and child:0.05mg/kg iv push,increase bolus doses by 0.05mg/kg q2min,max dose:0.25mg/kg or 12mg Adult:6mg12 mg 12 mg 此课件下载可自行编辑修改，此课件供参考！此课件下载可自行编辑修改，此课件供参考！部分内容来源于网络，如有侵权请与我联系删除！感谢你的观看！部分内容来源于网络，如有侵权请与我联系删除！感谢你的观看！