总维生素D检测的重要性及临床意义优质课件.ppt

1、1血清总25OH维生素D检测的重要性及临床应用The Importance and Clinical Application of Total 25OH-D1维生素D营养状况的评判标准 2聊城地区育龄女性VD状况统计成人共 636人 VD10 26341.35%10VD20 31349.21%20VD30 375.82%VD30 233.62%3聊城地区儿童VD状况儿童统计364人 VD10 113.02%10VD20 65 17.86%20VD99.1 nmol/L)had a 62%lower risk of developing MS.postmenopausal women with

2、the highest total vitamin D intakes were at significantly lower risk of developing RA after 11 years of follow-up than those with the lowest intakes 8多发性硬化症与纬度的关系People living closer to the equator are at decreased risk of developing MSSimilar trends:cancer,hypertension9促进细胞分化、抑制增殖-维生素D降低肿瘤发生率 The a

3、ctive form of vitamin D,1,25-dihydroxyvitamin D,inhibits proliferation and stimulates the differentiation of cells.Holick MF.Vitamin D:importance in the prevention of cancers,type 1 diabetes,heart disease,and osteoporosis.Am J Clin Nutr.2004;79(3):362-371.10促进细胞分化、抑制增殖-维生素D降低肿瘤发生率111212维生素D:每个人、人生的每个阶段都要关注131415维生素D检测的临床应用 儿科：佝偻病、骨软化症、儿童骨骼发育不良、骨折、小儿精神抑郁、自闭症，疗效监测、预防维生素D中毒 产科:孕期和哺乳期维生素D检测，预防产科并发症和新生儿维生素D缺乏；预防产后骨质疏松症和抑郁症 -中华儿科学会推荐：妊娠3个月查25OHD，确定维生素D的补充剂量15维生素D营养状况的评判标准维生素D达到什么水平才能受益161718总结 维生素D缺乏是很普遍的 补充维生素D，不仅促进骨健康，且有益全身健康 维生素D理想水平是30-100ng/ml 补充维生素D应在检测指导下补充 检测的指标是总25-OH-D 实验室应选用合适的检测平台1819