心肌酶谱临床意义讲义课件.ppt

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10、ifelife Dedicate to excellenceDedicate to excellence HCY（同型半胱氨酸）临床意义： 高浓度的Hcy是冠状动脉疾病、脑血管疾病、外周血管疾病独立的危险因子！ 血Hcy增高与多种疾病相关,如动脉硬化相关疾病(冠心病、中风、糖尿病等),静脉栓塞,肾脏疾病,骨质疏松,老年性痴呆,肿瘤,妊娠并发症,习惯性流产及新生婴儿缺陷等。因此监测和降低同型半胱氨酸的浓度，具有十分重要的临床意义。 适用人群：高血压、高血脂、肾病（尤其是透析患者）、孕妇、老年性痴呆等Care forCare for lifelife Dedicate to excellenceD

11、edicate to excellence 科华HCY试剂盒特点：1.准确度：测定高低值质控，结果应在质控给定的范围内。2. 精密度：批内变异系数CV10%批间变异系数 CV15%。3.线性范围：样本浓度在3-50mol/L范围内，整个反应呈线性，r0.99。上述指标经国家认可的检测机构通过检测。Care forCare for lifelife Dedicate to excellenceDedicate to excellence Hs-CRPHs-CRP( (超敏超敏C C反应蛋白反应蛋白) )临床意义：临床意义： 用于心脑血管疾病危险性评估用于心脑血管疾病危险性评估! ! hs-CRP

12、并不是一种新的并不是一种新的CRP，其实是根据，其实是根据测定方法更敏感而命名测定方法更敏感而命名。临床常规测定普通。临床常规测定普通CRP的方法检测线性一般为的方法检测线性一般为3200mg/L，因缺乏较高的灵敏性已不足以预测心血管事件的，因缺乏较高的灵敏性已不足以预测心血管事件的危险。近年相继采用胶乳增强的免疫比浊法等技术大大提高了分析的灵敏度（检测低限为危险。近年相继采用胶乳增强的免疫比浊法等技术大大提高了分析的灵敏度（检测低限为0.0050.10mg/L不等），在低浓度不等），在低浓度CRP（如（如0.1510mg/L）测定范围内有很高的准确度。）测定范围内有很高的准确度。用这些方法所

13、进行测定的用这些方法所进行测定的CRP称为高敏感或超敏感称为高敏感或超敏感CRP，国内一般简称为超敏或高敏，国内一般简称为超敏或高敏CRP 。 血清血清CRPCRP水平，尤其是个体基础水平，尤其是个体基础CRPCRP水平是心肌梗死、中风、外周动脉疾病、无明显心血水平是心肌梗死、中风、外周动脉疾病、无明显心血管疾病、急性冠脉综合征患者及稳定型冠状动脉疾病（管疾病、急性冠脉综合征患者及稳定型冠状动脉疾病（CADCAD）患者的强有力的、独立的、预）患者的强有力的、独立的、预测性的危险因子。测性的危险因子。 正常人进行健康体检，可观察个体正常人进行健康体检，可观察个体CRPCRP的基础水平和动态变化，用的基础水平和动态变化，用于对将来发生心脑血管于对将来发生心脑血管事件进行风险预测。事件进行风险预测。Care forCare for lifelife Dedicate to excellenceDedicate to excellence 快乐工作快乐工作享受生活享受生活