耳鼻咽喉科学英文版课件 inflammtory diseases of nasal cavity.ppt

1、Department of Otolaryngology, Affiliated Ninth People s Hospital of Shanghai Jiaotong University, School of Medicine Wang Peihuacause of disease1. systemic factors:systemic dieases, malnutrition, endocrine disturbance, immunodeficiency 2. local factor: acute rhinitis, nasal sinusitis, anatomic abnor

2、malities, some naristillaes 3. occupational and environmental factorsInflammatory cell infiltration without mucosal hyperplasiamucosal and submucosal extensive fibroplasiaARIA Classification 季节性季节性 常年性常年性 间歇性间歇性 间歇性间歇性 持续性持续性 持续性持续性 中重度中重度 轻度轻度 中重度中重度 轻度轻度 中重度中重度 轻度轻度 中重度中重度 轻度轻度Exuviae and feathers

3、 of animals Allergic rhinitis -cascade reactionAllergic rhinitis -cascade reactionClin Drug Invest 2005; 25 (3): 153-164Allergic rhinitisAllergic rhinitisAllergic rhinitisTreatment To advoid allergensPharmacotherapyImmunotherapyOthers:laser, radiofrequency ablation , surgery and so on. Treatment to

4、AR (ARIA)PharmacotherapyLocal application of corticosteroid hormone is the first choice e.g.e.g. BeclometasoneBeclometasone DipropionateDipropionate, , fluticasonefluticasone, , budesonidebudesonide, , momestasonemomestasone furoatefuroate. . combinationcombination：antihistaminicsantihistaminics, ,

5、peroralperoral corticosteroids, corticosteroids, mastocytemastocyte inhibitor, inhibitor, antileukotrieneantileukotriene Directions of corticosteroid nasal spray:Directions of corticosteroid nasal spray:persistent ARpersistent AR：decrease progressively to minimum decrease progressively to minimum ma

6、intenance dosemaintenance doseintermittent ARintermittent AR：use it 1 month before the period of use it 1 month before the period of onset, for 3-4 years.onset, for 3-4 years. coryzacoryza professionalisprofessionalis：long-term uselong-term useCauses of treatment failure: anatomic abnormality, sinusitis, polyps, fugus and so on.Van Cawenberge P, et al.Eropean Academy of Allergology and Clinical Immnology. Allergy, 2000;55(2):p116-34Chronic congestion of nasal mucosa, dark red or pallor.Chief method: pharmacotherapy.