卵巢癌-Ovarian-Cancer- 课件.ppt
- 【下载声明】
1. 本站全部试题类文档,若标题没写含答案,则无答案;标题注明含答案的文档,主观题也可能无答案。请谨慎下单,一旦售出,不予退换。
2. 本站全部PPT文档均不含视频和音频,PPT中出现的音频或视频标识(或文字)仅表示流程,实际无音频或视频文件。请谨慎下单,一旦售出,不予退换。
3. 本页资料《卵巢癌-Ovarian-Cancer- 课件.ppt》由用户(三亚风情)主动上传,其收益全归该用户。163文库仅提供信息存储空间,仅对该用户上传内容的表现方式做保护处理,对上传内容本身不做任何修改或编辑。 若此文所含内容侵犯了您的版权或隐私,请立即通知163文库(点击联系客服),我们立即给予删除!
4. 请根据预览情况,自愿下载本文。本站不保证下载资源的准确性、安全性和完整性, 同时也不承担用户因使用这些下载资源对自己和他人造成任何形式的伤害或损失。
5. 本站所有资源如无特殊说明,都需要本地电脑安装OFFICE2007及以上版本和PDF阅读器,压缩文件请下载最新的WinRAR软件解压。
- 配套讲稿:
如PPT文件的首页显示word图标,表示该PPT已包含配套word讲稿。双击word图标可打开word文档。
- 特殊限制:
部分文档作品中含有的国旗、国徽等图片,仅作为作品整体效果示例展示,禁止商用。设计者仅对作品中独创性部分享有著作权。
- 关 键 词:
- 卵巢癌-Ovarian-Cancer- 课件 卵巢癌 Ovarian Cancer
- 资源描述:
-
1、Ovarian Cancer DI WEN M.D., Ph.D., Professor & Chairman Department Of Obstetrics & Gynecology Renji Hospital Affiliated to SJTU School of Medicine22006-11-1 七年制Ovarian CancerGeneral IntroductionvOvarian tumors are commonest between 30 and 60. vThey are particularly liable to be or to become malignan
2、t.vIn their early stages, they are asymptomatic and painless.vThey may grow to a large size.v1.4% lifetime risk of ovarian cancer32006-11-1 七年制Ovarian CancerRisk FactorsvFamily historyOvarian cancerBreast cancerColon cancervGenetic factorsvOlder agevCaucasianvMore menstrual circles during lifetime (
3、Ovulation induction)42006-11-1 七年制Ovarian CancerIncidencevNearly 25% of all ovarian neoplasm are malignant.vApproximately 80 of them are primary growths of the ovary.vThe remainder being secondary,usually carcinomata.52006-11-1 七年制Ovarian CancersymptomsvLack of any specific symptoms, ovarian tumors
4、are often large by the time the doctor is consulted.vMenstrual function is seldom upset, and any irregularity is attributed to the patients time of life.62006-11-1 七年制Ovarian CancersymptomsvIncreased abdominal size72006-11-1 七年制Ovarian CancersymptomsPressure symptomsGastro-intestinal symptoms (Bloat
5、ing)Urge to urinateplevic pain (a dull pain in the lower abdomen)Very large tumors may cause respiratory embarrassment and edema or varicosities in the legs, and a characteristic ovarian cachexia develops.82006-11-1 七年制Ovarian CancerCLINICAL FEATURES OF OVARIAN TUMOURS92006-11-1 七年制Ovarian CancerCLI
6、NICAL FEATURES OF OVARIAN TUMOURS102006-11-1 七年制Ovarian CancerCLINICAL FEATURES OF OVARIAN TUMOURS112006-11-1 七年制Ovarian CancerGeneral Rule An experienced examiner will recognize an ovarian tumor mainly because ovarian tumor is, in the circumstances, the most likely diagnosis. All abdominal swelling
7、s should be subjected to ultrasound and X-ray examination.DIFFERENTIAL DIAGNOSISDIFFERENTIAL DIAGNOSIS122006-11-1 七年制Ovarian CancerDIFFERENTIAL DIAGNOSISDIFFERENTIAL DIAGNOSIS132006-11-1 七年制Ovarian CancerASCITES A fluid thrill may be elicited from an ovarian cyst, and ascites and tumor may coexist;
8、but as a rule the distinction should be easily made.DIFFERENTIAL DIAGNOSISDIFFERENTIAL DIAGNOSIS142006-11-1 七年制Ovarian CancerUterine Fibroids A large midline intramural fibroid may b e i m p o s s i b l e t o distinguish from a solid ovarian tumor until the abdomen is opened and an entirely differen
9、t s u r g i c a l p r o b l e m encountered.DIFFERENTIAL DIAGNOSISDIFFERENTIAL DIAGNOSIS152006-11-1 七年制Ovarian CancerDIFFERENTIAL DIAGNOSISDIFFERENTIAL DIAGNOSIS162006-11-1 七年制Ovarian CancerDIFFERENTIAL DIAGNOSISDIFFERENTIAL DIAGNOSIS172006-11-1 七年制Ovarian CancerDIFFERENTIAL DIAGNOSISDIFFERENTIAL DI
10、AGNOSIS182006-11-1 七年制Ovarian CancerHistological Classification Most tumors arise from the ovarian stroma and germinal epithelium. The embryonic coelom from which that epithelium develops also gives rise to the Mullerian duct from which develop the structures of the genital tract, and it is this com
11、mon origin which explains the great variety of epithelial patterns which are met with.192006-11-1 七年制Ovarian CancerPrimary Epithelial TumorvMucinous cystadenoma or cystadencarcinoma (of. Cervical epithelium).vSerous cystadenoma or cystadenocarcinoma (of . tubal epithelium).vEndometrioma or Endometri
12、oid carcinoma (of. Endometrium).vClear cell carcinoma.vBrenner tumour.202006-11-1 七年制Ovarian CancerOvarian Germ Cell TumorFibroma or sarcoma.Dysgerminoma.Teratoma.Gonadoblastoma.Yolk sac tumour.Carcinoid.Thyroid tumour Choriocarcinoma212006-11-1 七年制Ovarian CancerGonadal Sex Cord Stromal TumorGranulo
13、sa cell tumour.Thecoma.Sertoli-Leydig cell tumor (Arrhenoblastoma).Hilar cell tumour.Lipoid cell tumour.222006-11-1 七年制Ovarian CancerKrukenberg Tumor There is one well-known secondary tumour of the ovary, the krukenberg t u m o u r, a s e c o n d a r y o f a stomach carcinoma.232006-11-1 七年制Ovarian
14、CancerMucinous cystadenoma A u n i l o c u l a r o r multilocular cyst of ovary lined by tall columnar epithelium resembling that of the cervix or large intestine. It is usually large and may reach immense proportions, occupying the whole peritoneal cavity and compressing other organs. It may occur
15、at any age.242006-11-1 七年制Ovarian CancerOVARIAN TUMOURSOVARIAN TUMOURS -MUCINOUS CYSTADENOMAMUCINOUS CYSTADENOMA252006-11-1 七年制Ovarian Cancer SEROUS CYSTADENOMA A unilocular or multilocular cyst lined by epithelium similar to the fallopian tube. They are the most common benign epithelial tumors and
16、form 20% of all ovarian neoplasm. In 10% of cases they are bilateral. It is uncommon to find them large than a fetal head. 262006-11-1 七年制Ovarian CancerOVARIAN TUMORSOVARIAN TUMORS -SEROUS CYSTADENOMA -SEROUS CYSTADENOMA272006-11-1 七年制Ovarian CancerSerous cystadenocarcinoma This is by far the common
17、est primary carcinoma, accounting for 60% of all cases, and in over half the cases it is bilateral. The cysts are always of papillary type and the epithelium burrowing through the capsule produces papillary processes on the serous surface. Extension of the growth to the pelvis and adjacent organs fi
18、xes the tumor. Ascites is always present.282006-11-1 七年制Ovarian CancerEndometrioid Carcinoma of the Ovary It is now recognized that carcinoma of the ovary may be of endometrial type, sometimes arising in endometrioma. Attacks of pain, unusual with ovarian cancer, are common. Sometimes there is uteri
19、ne bleeding in post-menopausal cases.292006-11-1 七年制Ovarian CancerEndometrioid Carcinoma of the Ovary Usually the lesion is cystic and chocolate brown in color. If such a cyst ruptures spontaneously, malignancy should be suspected. The histology varies as in uterine carcinoma. It may be a well-diffe
20、rentiated adenocarcinoma, an adeno-acanthoma, mucinous adenocarcinoma or clear-celled carcinoma.302006-11-1 七年制Ovarian CancerFibromav This is composed of fibrous tissue and resembles fibromata found elsewhere. It is most common in the elderly and accounts for 4-5% of all ovarian neoplasm.vThe fibrom
21、a is believed by many to be a thecoma which has undergone fibrous transformation. It is sometimes associated with Meigs syndrome.312006-11-1 七年制Ovarian CancerDysgerminoma This is the only solid o v a r i a n t u m o r o f characteristic appearance. Usually ovoid with a smooth capsule, it is of rubbe
展开阅读全文