新型给药系统研发进展.docx

1、新型给药系统研发进展2017 年 5 月 5 日、12 日要求：1、人员和时间：每组 2 人，文献讲解 5-8 分钟2、讲解内容：（1）杂志简介；（2）作者研究团队简介；（3）文献内容：研究背景和意义、数据分析和结论；（4）个人观点：文献值得学习或不足的方面分析。3、展示文献:1)Freeze concentration-induced PLGA and polystyrene nanoparticle aggregation:Imaging and rational design of lyoprotection. J Control Release. 2017, 248:125-132.2

2、)How do megakaryocytic microparticles target and deliver cargo to alter the fateof hematopoietic stem cells? J Control Release 2017, 247: 118.3)Self-assembly of green tea catechin derivatives in nanoparticles for oral lycopenedelivery. J Control Release 2017, 248:117-124.4)Single ocular injection of

3、 a sustained-release anti-VEGF delivers 6 monthspharmacokinetics and efficacy in a primate laser CNV model. J Control Release2016, 244:1-13.5)Crossing the blood-brain barrier: Glutathione-conjugated poly(ethylene imine) forgene delivery. J Control Release 2016, 241:1-14.6)Tumour-associatedmacrophage

4、sactasaslow-releasereservoirofnano-therapeutic Pt(IV) pro-drug. Nat Commun. 2015, 6:8692.7)Theranostic barcoded nanoparticles for personalized cancer medicine. NatCommun. 2016, 7:133258)Animmunostimulatorydual-functionalnanocarrierthatimprovescancerimmunochemotherapy. Nat Commun. 2016, 7:133439)Augm

5、enting drugcarrier compatibility improves tumour nanotherapy efficacy.Nat Commun. 2016, 7: 1344310) Cell type-specific delivery of short interfering RNAs by dye-functionalisedtheranostic nanoparticles. Nat Commun. 2014, 5: 556511) A smart and versatile theranostic nanomedicine platform based on nano

6、porphyrin.Nat Commun. 2014, 5: 471212) The battle of nano paclitaxel. Adv Drug Deliv Rev. 2017 Feb 28.13) Red blood cells: Supercarriers for drugs, biologicals, and nanoparticles andinspiration for advanced delivery systems. Adv Drug Deliv Rev. 2016,106:88-103.14) Extracellular vesicles for drug del

7、ivery. Adv Drug Deliv Rev. 2016, 106:148-156.15) Dry powder inhalable formulations for anti-tubercular therapy. Adv Drug DelivRev. 2016, 102:83-101.16) Tumor penetrating peptides for improved drug delivery. Adv Drug DelivRev. 2016, Apr 1.17) Enzyme-CleavablePolymericMicellesfortheIntracellularDelive

8、ryofPro-Apoptotic Peptides. Mol Pharm. 2017 Mar 9.18) Investigation into the Biological Impact of Block Size on Cathepsin S-degradableHPMA Copolymers. Mol Pharm. 2017 Mar 6.19) Biocompatible Injectable Hydrogel with Potent Wound Healing and AntibacterialProperties. Mol Pharm. 2017 Mar 6.20) Reloadab

9、le Silk-Hydrogel Hybrid Scaffolds for Sustained and Targeted Deliveryof Molecules. Mol Pharm. 2016, 13:4066-4081.21) Light Control of Insulin Release and Blood Glucose Using an InjectablePhotoactivated Depot. Mol Pharm. 2016, 13: 3835-3841.22) One-week in vivo sustained release of a peptide formulat

10、ed into in situ formingimplants. Int J Pharm. 521:357-360.23) Enhanced ocular efficacy of topically-delivered dorzolamide with nanostructuredmucoadhesive microparticles. Int J Pharm. 522:66-73.24) Amorphization within the tablet: Using microwave irradiation to form a glasssolution in situ. Int J Pharm. 519: 343-351.25) The Development of Self-nanoemulsifying Liquisolid Tablets to Improve theDissolution of Simvastatin. AAPS PharmSciTech. 2017 Feb 24.