1、 11 Others11 Others 一、The contents of others 1、Characteristics：包括药物的药理作用特点、疗效、剂量及药物代谢。eg1：patent：专利 （CA.中有专利索引 patent index）non-narcotic non 非-否定词前缀Properties:eg2：抗代谢的 anti-metabolism 叶酸 folic acid FH4 四氢叶酸 肿瘤 tumor 化疗 chemotherapy/放疗 radiotherapy eg3：本品毒性小，副作用极为轻微 Toxicity is low,Side effects are m
2、inimal.临床效果：clinical effect eg4：抗炎作用：anti-inflammatoryPharmacokinetics：include：metabolism、absorption、distribution and elimination.*eg7：英汉互译，要求学生掌握其中的六个专业术语 The absolute bioavailability of the drug im.Or sc.Is approximately 70%.It peak plasma concentration is attained within one hour and it has half-
3、life of elimination of 70-90 minutes.Up to 95%of the dose is excreted via the kidneys,2%as unchanged drug,.The apparent volume of distribute is 0.15-0.31/kg and protain binding 30-40%.4 overdosage：include the effect,signs and sympotoms,treatment of overdosage.5 interaction or drug interaction 词缀：int
4、er 相互 each other eg11：Temaril tablets should not be administrated with 4 hours of medications containing Mgnesium,aluminium,or iron salts as interference with absorption my occur.eg12：Simultaneous consumption of alcohol can impair reaction time,eg in traffic or during reaction of machines.At higher
5、dosage of the drug with simultaneous administration of blood pressure lowering medicaments the effect of the latter can be potentiated.6 Validity Validity storage life Exp.date shelf life Stable Stability：activity toxicityeg15：Exp：18months（Expiry date is printed on the vial label.）二、other terms1、参考文
6、献：reference：refer（v.）=literature学习书写论文的一般格式：论文标题/摘要/关键词/参考文献 title/abstract/key words/reference 2、临床数据：clinical data =clinical effect 3、耐受性：tolerance-tolerate 耐药性：resistance-resistant4、批号：Batch No.5、制造：made in manufacture 实验研究型论文（一）内容结构（一）内容结构1、中文标题2、作者3、中文摘要、关键词（35个）4、正文：（1）引言 （2）材料与方法 （3）结果与数据处理 （
7、4）讨论 （5）结论 5、参考文献HPLCHPLC测定小儿清肺止咳泡腾片中黄芩苷的含量XXXXXX（浙江医药高等专科学校，浙江 宁波 315100）摘要摘要：目的目的：建立一种用高效液相色谱法测定小儿清肺止咳泡腾片中黄芩苷含量的方法。方法方法:高效液相色谱柱为：Diamonsil C18柱（5m，250 mm4.6mm）；流动相：甲醇-水-甲酸（50500.2）；检测波长：280nm；流速：1.2mlmin；结果结果：黄芩苷在17.2172g/ml的范围内与峰面积呈良好的线性关系。平均回收率97.97%；RSD为2.18%。结论结论：该方法快速，准确，专属性好，灵敏度高，可用于小儿清肺止咳泡腾
8、片中黄芩苷的含量测定。关键词：关键词：高效液相色谱法；黄芩苷；小儿清肺止咳泡腾片；含量测定Determination of Baicalin in Xiaoer Qingfei Zhike Determination of Baicalin in Xiaoer Qingfei Zhike Effervescent Tablet by HPLCEffervescent Tablet by HPLCAbstract:Objective:Abstract:Objective:To establish a content determination method of baicalin in Xiao
9、er Qingfei Zhike Effervescent Tablet by HPLC.Methods:Methods:Results:Results:Conclusion:Conclusion:Key wordsKey words：HPLC；Baicalin；Xiaoer Qingfei Zhike Effervescent Tablet；Assay文献综述型毕业论文1、中文标题2、作者3、中文摘要、关键词（35个）4、正文：（1）引言 （2）正文主要内容 （3）展望5、参考文献三、生产厂家的表示方法：制药厂：Pharmaceutical factory制药有限公司：pharmaceuti
10、cal CO.，Ltd制药股份有限公司：pharmaceutical Inc.（Incorperator）四、homework按照标准格式，书写“Aspirin”英文药品说明书。The structure of Egnlish package insertDrug name：Trade name Generic name Chemical nameDescription：Pharmacological action：Indication：Contraindication：Dosage and Administration：Adverse Reaction：Precaution：Storage：
11、Package：Others：Batch No.Validity manufacture1 AngisedvDrug name：trade name：Angised （心绞痛 Angina）generic name：glyceryl trinitrate 说明：（gly甘油 -yl 基团 tri三 -ate 酸或酯，此处为酯）chemical name：glyceryl trinitratevDescription：Each white,round,flat,uncoated tablets is scored and impressed说明：“Wellcom P2A”and contains
12、 500 micrograms glyceryl for sublingual administration.vAnalysis：color：white shape：round and flat preparation：uncoated and scored tablet indigrents：500mg glyceryl trinitrate administration：sl.vPharmacological action：Angised redistributes blood flow Angised also reduced oxygen demand The fall in arte
13、rial pressure will also reduce myocardial O2 demand.（It can reduce myocardial O2 demand.）Reduction of preload.词缀：pre-do sth before eg.preview 预习 re-do sth again or after eg.review 复习vIndication：（1）acute attacks of angina pectoris （2）for the prophylaxis of such attack （3）pulmonary oedemavContra-indic
14、ation：angina caused by hypertrophic obstructive cardiomyopathy.词缀：myo-肌肉 cerebral haemorrhage or head trauma 词缀：ha(e)mo-血vDosage and Administration：（1）Administration：sublingual （2）Dosage：require：Treatment of acute attacks One tablet should be given every 3 minite.The minimum effective dose.Patients
15、should keep sitting positionvAdverse reaction：large dosage may result in vomiting,cyanosis,restlessness,impairment of respiration,methaemoglobinaemia.vPrecaution：vStorage：below 25.Protect from lightvPackage：in glass containers closed with a foil-lined cap no cotton-woolvOthers：v pharmacokinetics：1、W
16、hy ndoes not Angised be taken by orally?Glyceryi trinitrate is readily absorbed in the buccal mucosa but is rapidly metabolized.It is also readily absorbed in G-I tract but owing to the extensive first-pass metabolism in the liver.Its bioavailability is reduced.v2、hydrolysis process：glyceryl trinitr
17、ate-glyceryl dinitrate-glyceryl mononitratev 3、metabolism time：peak plasma level appears within 4 minute at least half of the intact（untouched、unchanged）drug is cleared from the blood in 13 minute.vDrug interaction：The risks of hypotension and syncope with use of Angised may be ebhanced by the effec
18、ts of alcohol.vOverdosage：Methaemoglobinaemia may be treated by iv.methylene blue.（词缀：methyl-甲基;-ene 烯烃）vBatch No.：略 vvalidity：3 yearsvmanufacture：Wellcom Foundation Ltd London.一、The backgroud of“-xacin”喹啉羧酸类：Norfloxacin:85年上市 Ciprofloxacin:Temaril Pefloxacin:Lomefloxacin:Sparfloxacin:Ofloxacin：Teri
19、vidThe informations about Ciprofloxacin Drug name：Trade name：Temaril Generic name：Ci pro flo xacin 环 丙 沙星 Chemical name:略 Description：Infusion：Temaril：100,clear,almost colorless to pale yellow silution containing 127.2mg Ciprofloxacin lactate（equivalent to 100mg Ciprofloxacin）in 50ml solution.Tablet
20、：Temaril：250,white,scored,film-coated tablets marked on one side with 250,each tablets containing 291.5mg Ciprofloxacin hydrochloride monohydrate.Question：Why Ciprofloxacin Infusion-lactate Tablet-hydrochloride Pharmacological action：The drug is a synthetic（TCM.extract）,4-quinolone derivative with b
21、actericidal activity against a wide range of G+and G-.(Points：Terms：bactericidal activity/wide range)The drug is indicated for the treatment of single infections or mixed infections caused by two or more susceptible organisms.(Points：Drill：-be indicated for the treatment-)Terms：single infection mixe
22、d infection susceptible organisms It may be used for infections caused by organisms resistant to other antibiotics,including：aminoglycoside,penicillin（-lactam）and cephalosporins.Points：氨基糖苷aminoglycoside 盘尼西林（青霉素）penicillin -内酰胺 -lactam 头孢菌素 cephalosporins 耐药性 resistant Microbiologic：（略）常见致病菌名称，以后工作
23、中遇到作为资料查阅.Indication：sever systemic infection Respiratory tract infection Ear,nose and throat infections Urinary tract infections skin and soft tissue infection Contraindication：Dosage and Administration：Administration：Orally or Infusion according to the different dosage form Dosage range：for adult
24、is 250-750mg twice daily.Adverse reaction：Precaution：Storage Package：Others：Batch No.：validity：manufacture：作业：请按照教材自己补充完全。Temarilv【药品名称】：【商品名称】：替马利尔 v 【通用名称】：环丙沙星v【性状】：本品为白色有刻痕的薄膜片。【药理作用】：本品是一种合成的4-喹喏酮 的衍生物，对广泛的G+和G-具有杀菌 作用。v【适应症】：本品适用于治疗由敏感细菌 引起的下列感染。v【禁忌症】：对本品以及其他喹喏酮类药物 过敏的患者忌用。v【剂量和用法】：成人剂量范围为100
25、200 mg，每日两次。v【不良反应】：本品一般耐受良好，最常报 道的不良反应有恶心，呕吐，皮疹等。v【注意事项】：孕妇及哺乳期妇女应慎用。避免儿童接触本品。v【贮藏】：25以下避光保存。v【包装】：铝塑条状包装，每条10片。v【其它】：【有效期】2年。【批准文号】国药准字第(00000001)号 【生产企业】浙江省新昌药业有限公司 Angised说明书说明书v【药品名称】：【商品名称】安吉斯特 【通用名称】硝酸甘油v【性状】：本品为白色扁圆形片剂。v【药理作用】：（1）血流量的再分布 （2）降低耗氧量 （3）降低前负荷v【适应症】：心绞痛的急性发作。v【禁忌症】：脑出血或头部外伤的患者禁 用本品。v【剂量和用法】：舌下含服。每三分钟给药 一次，每次一片。v【不良反应】：最常见的不良反应是：呕 吐，不安，呼吸受损。v【注意事项】：孕妇及哺乳期妇女应慎用。v【贮藏】25以下避光保存。v【包装】玻璃瓶,不得含有棉绒。v【其它】【有效期】3年 【批准文号】国药准字第（00000002）号 【生产企业】浙江省大红鹰药业有限公司
